29th July 2010
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BIOLOGY - DNA
84951
An Assessment of the Utility of Single Nucleotide Polymorphisms (SNPs) for Forensic Purposes
Gill-P
The Forensic Science Service; Trident Court; 2960 Solihull Parkway; Birmingham Business Park; Birmingham; B37 7YN; UK
INT-J-LEG-MED; 2001; V114; P204-210

This paper assesses the use of single nucleotide polymorphisms (SNPs) for forensic analysis. It demonstrates that relatively small arrays of approximately 50 loci are comparable to existing short tandem repeat (STR) multiplexes. A quantitative test is, however, a prerequisite for mixture interpretation. In addition, as the mixture proportion becomes low, it will be necessary to distinguish between the allele and the background. Relatively small biallelic arrays are also suitable for distinguishing between closely related individuals such as brothers.

Subject Heading

BIOLOGY - DNA

Abstract Number

84951

Title - in English

An Assessment of the Utility of Single Nucleotide Polymorphisms (SNPs) for Forensic Purposes

Author Name(s)

Gill-P

Correspondance Address

The Forensic Science Service; Trident Court; 2960 Solihull Parkway; Birmingham Business Park; Birmingham; B37 7YN; UK

Abbreviated journal title / Publication year / Volume number / Page numbers

INT-J-LEG-MED; 2001; V114; P204-210

Abstract - in English

This paper assesses the use of single nucleotide polymorphisms (SNPs) for forensic analysis. It demonstrates that relatively small arrays of approximately 50 loci are comparable to existing short tandem repeat (STR) multiplexes. A quantitative test is, however, a prerequisite for mixture interpretation. In addition, as the mixture proportion becomes low, it will be necessary to distinguish between the allele and the background. Relatively small biallelic arrays are also suitable for distinguishing between closely related individuals such as brothers.

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